HCID 13338732, compound → HCID 13338733, compound

HRID 2417849Notes

Reaction equation

HRID 2417849 reaction equation
[N:1]([CH:4]1[CH2:12][CH2:11][CH2:10][CH2:9][C:8]2[CH:13]=[CH:14][CH:15]=[CH:16][C:7]=2[N:6]([CH2:17][C:18]([O:20][CH2:21][CH3:22])=[O:19])[C:5]1=[O:23])=[N+]=[N-]>C(O)C.[Pd]>[NH2:1][CH:4]1[CH2:12][CH2:11][CH2:10][CH2:9][C:8]2[CH:13]=[CH:14][CH:15]=[CH:16][C:7]=2[N:6]([CH2:17][C:18]([O:20][CH2:21][CH3:22])=[O:19])[C:5]1=[O:23]

Participants

4

Reactant 1

HCID 13338732HCID 13338732, compound

Product 1

HCID 13338733HCID 13338733, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A solution of 3-azido-1-ethoxycarbonylmethyl-1,3,4,5,6,7-hexahydro-1-benzazonin-2-one (5.0 g) in ethanol (500 ml) is hydrogenated at atmospheric pressure using 10% palladium on charcoal (0.7 g) as catalyst. The catalyst is filtered off and the solvent removed under reduced pressure to give 3-amino-1-ethoxycarbonylmethyl-1,3,4,5,6,7-hexahydro-1-benzazonin-2-one.

Workup

  1. filtrationThe catalyst is filtered off
  2. customthe solvent removed under reduced pressure

Sources & evidence

ORD record
ord-851f5cd2d8514c558929b6523b29085e
Source dataset
uspto-grants-1984_09
Patent number
US04470988

Reaction notes

Loading…