Sodium → HCID 54169835, compound

Participants

Reaction Steps

To a solution of 5.1 g of 3-mercaptophenyl 2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)-1-thio-β-D-glucopyranoside in 50 ml of methanol was added 0.15 g of sodium spheres. The reaction was stirred 3 hours, concentrated in vacuo and warmed with 50 ml of methanol:water (1:1). This reaction was filtered, the filtrate stirred with Dowex® 50WX8 resin and refiltered. This filtrate was concentrated in vacuo, giving 2.7 g of the desired intermediate as a yellow solid, [α]D26 =+81°±1° (0.818%, methanol).

Provenance & Evidence