HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropylamine → 4-[3-(1-Methylethyl)aminopropyl]phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropylamine | HCID 6363 | — |
| Reactant | 4-[2-(1-Methylethyl)aminoethyl]phenol | HCID 417599 | — |
| Reactant | 4-(3-Bromopropyl)phenol | HCID 14817036 | — |
| Product | 4-[3-(1-Methylethyl)aminopropyl]phenol | HCID 20446957 | 97.9% |
Reaction Steps
Under the conditions outlined above for the preparation of 4-[2-(1-methylethyl)aminoethyl]phenol, 4-(3-bromopropyl)phenol was reacted with isopropylamine. The crude product was distilled in a Kugelrohr apparatus (150°; 1 mm) and the distillate was crystallized from ether to give 4-[3-(1-methylethyl)aminopropyl]phenol (97.9% pure by gas chromatography).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04471116 |
| Source dataset | uspto-grants-1984_09 |
| ORD ID | ord-dd2f28a8c0d1483faea80e8d534fd750 |
| Source note | uspto-grants-1984_09 |