3,4-Dimethoxy-1,2,5-thiadiazole 1,1-dioxide → HCID 178434785, compound

HRID 2418079Notes

Reaction equation

HRID 2418079 reaction equation
CO[C:3]1[C:7](OC)=[N:6][S:5](=[O:11])(=[O:10])[N:4]=1.[CH3:12][N:13]([CH2:15][C:16]1[S:20][C:19]([CH2:21][S:22][CH2:23][CH2:24][NH2:25])=[CH:18][CH:17]=1)[CH3:14].COC1C=NS(=O)(=O)N=1.[CH3:35][C:36]1[C:37]([CH2:41][S:42][CH2:43][CH2:44][NH2:45])=[N:38][O:39][N:40]=1>>[CH3:14][N:13]([CH2:15][C:16]1[S:20][C:19]([CH2:21][S:22][CH2:23][CH2:24][NH:25][C:3]2[C:7]([NH:45][CH2:44][CH2:43][S:42][CH2:41][C:37]3[C:36]([CH3:35])=[N:40][O:39][N:38]=3)=[N:6][S:5](=[O:11])(=[O:10])[N:4]=2)=[CH:18][CH:17]=1)[CH3:12]

Participants

5

Reactant 4

HCID 122305383,4-Dimethoxy-1,2,5-thiadiazole 1,1-dioxideHCID 129139512-(5-Dimethylaminomethyl-2-thienylmethylthio)ethylamineHCID 131028982-[(4-Methyl-1,2,5-oxadiazol-3-yl)methylthio]ethylamineHCID 867396304-Methoxy-1,2,5-thiadiazole 1,1-dioxide

Product 1

HCID 178434785HCID 178434785, compound

Procedure

When a suspension of 3,4-dimethoxy-1,2,5-thiadiazole 1,1-dioxide is reacted with an equimolar amount of 2-[(5-dimethylaminomethyl-2-thienyl)methylthio]ethylamine and the resultant 3-55 2-[(5-dimethylaminomethyl-2-thienyl)methylthio]ethylamino}-4-methoxy-1,2,5-thiadiazole 1,1-dioxide is treated with 2-[(4-methyl-1,2,5-oxadiazol-3-yl)methylthio]ethylamine [prepared in Example 58, Step B], the title compound is thereby produced.

Sources & evidence

ORD record
ord-7609ccde3b8d4cae8ce8cf2c1b8fbb76
Source dataset
uspto-grants-1984_09
Patent number
US04471122

Reaction notes

Loading…