5-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furanmethanamine → HCID 178483226, compound

HRID 2418081Notes

Reaction equation

HRID 2418081 reaction equation
CO[C:3]1[C:7](OC)=[N:6][S:5](=[O:11])(=[O:10])[N:4]=1.[CH3:12][N:13]([CH2:15][C:16]1[O:20][C:19]([CH2:21][S:22][CH2:23][CH2:24][NH2:25])=[CH:18][CH:17]=1)[CH3:14].[O:26]1[CH:30]=[CH:29][C:28]([CH2:31][S:32][CH2:33][CH2:34][NH2:35])=[N:27]1>>[CH3:14][N:13]([CH2:15][C:16]1[O:20][C:19]([CH2:21][S:22][CH2:23][CH2:24][NH:25][C:7]2[C:3]([NH:35][CH2:34][CH2:33][S:32][CH2:31][C:28]3[CH:29]=[CH:30][O:26][N:27]=3)=[N:4][S:5](=[O:10])(=[O:11])[N:6]=2)=[CH:18][CH:17]=1)[CH3:12]

Participants

4

Reactant 3

HCID 1622035-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furanmethanamineHCID 122305383,4-Dimethoxy-1,2,5-thiadiazole 1,1-dioxideHCID 129234172-((Isoxazol-3-ylmethyl)thio)ethanamine

Product 1

HCID 178483226HCID 178483226, compound

Procedure

When a methanolic suspension of 3,4-dimethoxy-1,2,5-thiadiazole 1,1-dioxide is reacted with one equivalent of 2-[(5-dimethylaminomethyl-2-furyl)methylthio]ethylamine according to the procedure described in Example 17, Step A, and the resultant product is treated with one equivalent of 2-[(3-isoxazolylmethylthio]ethylamine, the title compound is thereby produced.

Sources & evidence

ORD record
ord-ed4700801a7d47618f44177dfafbdebd
Source dataset
uspto-grants-1984_09
Patent number
US04471122

Reaction notes

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