HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → (3beta,5beta,15alpha,16alpha)-15,16-Dihydro-3,5-dihydroxy-3'H-cycloprop(15,16)androsta-6,15-dien-17-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 70505457 | HCID 70505457 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | (3beta,5beta,15alpha,16alpha)-15,16-Dihydro-3,5-dihydroxy-3'H-cycloprop(15,16)androsta-6,15-dien-17-one | HCID 13075974 | — |
Reaction Steps
A solution of 3β-acetoxy-5-hydroxy-15β,16β-methylene-5β-androst-6-en-17-one in 300 ml of methanol is stirred with 15 g of potassium carbonate for 30 minutes at room temperature. The reaction solution is diluted with diethyl ether, washed with water, dried, and evaporated, thus obtaining 27 g of 3β,5-dihydroxy-15β,16β-methylene-5β-androst-6-en-17-one, mp 187°-190° C., (acetone).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04472310 |
| Source dataset | uspto-grants-1984_09 |
| ORD ID | ord-5a4f1c622ea847a395c032620fccb4fd |
| Source note | uspto-grants-1984_09 |