Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 15,16-Dihydro-3-hydroxy-3'H-cycloprop[15,16]androsta-5,15-dien-17-one | HCID 13075949 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 12834728 | HCID 12834728 | — |
Reaction Steps
A solution of 95 g of 3β-hydroxy-15β,16β-methylene-5-androsten-17-one in 190 ml of pyridine was combined with 95 ml of acetic anhydride and stirred for 1.5 hours at 95° C. The precipitate obtained after pouring the mixture into ice water was filtered off, washed thoroughly with water, and dried, thus obtaining 107 g of 3β-acetoxy-15β,16β-methylene-5-androsten-17-one as a crude product. A sample extracted by boiling with diisopropyl ether melted at 140.5°-141° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04472310 |
|---|
| Source dataset | uspto-grants-1984_09 |
|---|
| ORD ID | ord-4470c4cfe19741ebb9c3b6a9b21f0210 |
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| Source note | uspto-grants-1984_09 |
|---|
