HCID 12106154, compound → HCID 12106155, compound

Participants

Reaction Steps

31 g of 3β-acetoxy-17,17-ethylenedioxy-15β,16β-methylene-5-androsten-7-one was reacted at room temperature within 1.5 hours in 310 ml of tetrahydrofuran with 31 g of lithium tri-tert.-butoxyaluminohydride. The reaction solution was diluted with diethyl ether, washed with potassium-sodium tartrate solution and water, dried, and evaporated. The residue was chromatographed on silica gel, thus obtaining 24.3 g 3β-acetoxy-17,17-ethylenedioxy-15β,16β-methylene-5-androsten-7β-ol, mp 199.5°-200° C. (acetone).

Provenance & Evidence