HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropanol → HCID 70505970, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | Acetone diisopropyl ether | HCID 22221350 | — |
| Reactant | HCID 88717966 | HCID 88717966 | — |
| Catalyst | Zinc | HCID 23994 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 70505970 | HCID 70505970 | 69.4% |
Reaction Steps
Analogously to Example 2, 13.5 g of 3β,17β-dibenzoyloxy-7α-chloro-5,6β-epoxy-15β,16β-methylene-5β-androstane is reacted in 130 ml of acetic acid and 130 ml of propan-2-ol with 49.5 g of zinc dust and worked up. Chromatography on silica gel yields 8.8 g of 3β,17β-dibenzoyloxy-15β,16β-methylene-5β-androst-6-en-5-ol, mp 223°-225° C. (acetone-diisopropyl ether).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04472310 |
| Source dataset | uspto-grants-1984_09 |
| ORD ID | ord-54c4495ebbf44f6e95b35d50daecb4fa |
| Source note | uspto-grants-1984_09 |