Tetrahydrofuran → HCID 56625789, compound

Participants

Reaction Steps

A solution of 21 g of 3β-hydroxy-15β,16β-methylene-5-androsten-18-one in 210 ml of tetrahydrofuran was stirred with 21 g of lithium tri-tert.-butoxyaluminohydride for 1 hour at room temperature. The mixture was then diluted with diethyl ether, washed with 2N sulfuric acid and water, dired, and evaporated, thus obtaining 19 g of 15β,16β-methylene-5-androstene-3β,17β-diol, used without further purification in the subsequent stage.

Provenance & Evidence