HCID 54511907, compound → HCID 13276500, compound

Participants

Reaction Steps

2.68 g of 3-(4-phenoxybenzoyl)acrylic acid were dissolved in 30 ml of diethyl ether, then 0.8 ml of thioacetic acid was added, and the mixture was stirred for 5 hours. After the diethyl ether was distilled off under reduced pressure, the residue was purified first by silica gel chromatography, eluted with a mixture of hexane and dichloromethane, then by recrystallization from a mixture of hexane and dichloromethane to give 2.96 g of 2-acetylthio-3-(4-phenoxybenzoyl)propionic acid.

Provenance & Evidence