HCID 13276506, compound → HCID 13276515, compound

HRID 2418166Notes

Reaction equation

HRID 2418166 reaction equation
C([S:4][CH:5]([CH2:11][C:12](=[O:27])[C:13]1[CH:18]=[CH:17][C:16]([O:19][C:20]2[CH:25]=[CH:24][C:23]([Cl:26])=[CH:22][CH:21]=2)=[CH:15][CH:14]=1)[C:6]([O:8][CH2:9][CH3:10])=[O:7])(=O)C.C(SC(CC(=O)C1C=CC(OC2C=CC=CC=2)=CC=1)C(OCC)=O)(=O)C>>[Cl:26][C:23]1[CH:22]=[CH:21][C:20]([O:19][C:16]2[CH:17]=[CH:18][C:13]([C:12]([CH2:11][CH:5]([SH:4])[C:6]([O:8][CH2:9][CH3:10])=[O:7])=[O:27])=[CH:14][CH:15]=2)=[CH:25][CH:24]=1

Participants

3

Reactant 2

HCID 13276506HCID 13276506, compoundHCID 13276511HCID 13276511, compound

Product 1

HCID 13276515HCID 13276515, compoundYield 75.9%

Procedure

The procedure in Example 26 was followed, except that 4.07 g of ethyl 2-acetylthio-3-[4-(4-chlorophenoxy)benzoyl]-propionate were used in place of ethyl 2-acetylthio-3-(4-phenoxybenzoyl)propionate, to give 2.77 g of ethyl 3-[4-(4-chlorophenoxy)benzoyl]-2-mercaptopropionate.

Sources & evidence

ORD record
ord-c64d7a4c505b4d56ac7a8fb8c3951490
Source dataset
uspto-grants-1984_09
Patent number
US04472316

Reaction notes

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