HuagongsheHuagongshe Chemistry Print Report · For research reference only
Broxyquinoline → HCID 13338828, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Broxyquinoline | HCID 2453 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Ethyl isocyanatoacetate | HCID 76283 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 13338828 | HCID 13338828 | — |
Reaction Steps
5,7-Dibromo-8-hydroxyquinoline (19.7 g), ethyl isocyanatoacetate (13.0 g) and triethylamine (6.58 g) were mixed in 200 ml of toluene and heated at reflux temperature for about 47 hours. The solution was cooled to room temperature and the desired ethyl N-(((5,7-dibromo-8-quinolinyl)oxy)carbonyl)glycinate was obtained as a white, crystalline solid, m.p. 129.5° C. (decomposition).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04472404 |
| Source dataset | uspto-grants-1984_09 |
| ORD ID | ord-352584ebf65840878a856e4511bd0af2 |
| Source note | uspto-grants-1984_09 |