HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chloro-8-hydroxyquinoline → HCID 13338832, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chloro-8-hydroxyquinoline | HCID 2817 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-Chloroethyl isocyanate | HCID 16035 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | HCID 13338832 | HCID 13338832 | — |
Reaction Steps
5-Chloro-8-hydroxyquinoline (35.9 g), 2-chloroethyl isocyanate (21.1 g), and triethylamine (2.02 g) were mixed in 400 ml of methyl ethyl ketone and heted at reflux temperature with stirring for about one hour. The reaction mixture, upon cooling to room temperature, yielded the desired 5-chloro-8-quinolinyl N-(2chloroethyl)carbamate as glistening, cream colored cystals, m.p. 146° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04472404 |
| Source dataset | uspto-grants-1984_09 |
| ORD ID | ord-7bbe69641fd54f4bb7b06d37cb63f803 |
| Source note | uspto-grants-1984_09 |