HCID 54239494, compound → HCID 54116286, compound

Participants

Reaction Steps

A solution of 50 g of (VII) in 1 l of glacial acetic acid and 30 ml of concentrated H2SO4 was hydrogenated in the presence of 5 g of 5% strength Pd/C at room temperature and under 5 bar, until the pressure remained constant. The catalyst was filtered off and the filtrate was made alkaline with dilute aqueous NaOH. The crude product was extracted with CH2Cl, and the solution was washed with H2O, dried over Na2SO4 and concentrated. Distillation of the residue gave 40 g of product of boiling point 200°-202° C./0.3 mbar.

Provenance & Evidence