HCID 20446182, compound → HCID 20446239, compound

HRID 2418377Notes

Reaction equation

HRID 2418377 reaction equation
[O:1]=[C:2]1[CH:10](SC)[C:9]2[C:4](=[C:5]([O:13][C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=3[O:20][CH3:21])[CH:6]=[CH:7][CH:8]=2)[NH:3]1>[Ni].C(O)C>[O:1]=[C:2]1[CH2:10][C:9]2[C:4](=[C:5]([O:13][C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=3[O:20][CH3:21])[CH:6]=[CH:7][CH:8]=2)[NH:3]1

Participants

4

Reactant 1

HCID 20446182HCID 20446182, compound

Product 1

HCID 20446239HCID 20446239, compoundYield 21.2%

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 702EthanolSolvent

Procedure

A mixture of 2-oxo-3-methylthio-7-(2-methoxyphenoxy)indoline (3.9 g) and Raney nickel (3.9 ml) in dried ethanol (70 ml) was treated in a similar manner to that of Preparation 15-(2) to give 2-oxo-7-(2-methoxyphenoxy)indoline (0.7 g), mp 145°-147° C.

Workup

  1. additionwas treated in a similar manner to that
  2. customof Preparation 15-(2)

Sources & evidence

ORD record
ord-7c671b4456934831aa3daeb16da13831
Source dataset
uspto-grants-1984_09
Patent number
US04472433

Reaction notes

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