HCID 20446191, compound → HCID 20446194, compound

HRID 2418397Notes

Reaction equation

HRID 2418397 reaction equation
[O:1]=[C:2]1[CH:10](SC)[C:9]2[C:4](=[C:5]([O:13][C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=3[Cl:20])[CH:6]=[CH:7][CH:8]=2)[NH:3]1>[Ni].O1CCOCC1>[O:1]=[C:2]1[CH2:10][C:9]2[C:4](=[C:5]([O:13][C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=3[Cl:20])[CH:6]=[CH:7][CH:8]=2)[NH:3]1

Participants

4

Reactant 1

HCID 20446191HCID 20446191, compound

Product 1

HCID 20446194HCID 20446194, compound

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 312751,4-DioxaneSolvent

Procedure

A mixture of thus obtained 2-oxo-3-methylthio-7-(2-chlorophenoxy)indoline and Raney nickel in dioxane was treated in a similar manner to that of Preparation 15-(2) to give 2-oxo-7-(2-chlorophenoxy)indoline.

Workup

  1. additionwas treated in a similar manner to that
  2. customof Preparation 15-(2)

Sources & evidence

ORD record
ord-97621e04d3174c34a929124db194532a
Source dataset
uspto-grants-1984_09
Patent number
US04472433

Reaction notes

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