HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Oxo-4-phenylbutyric acid → N-(1-carboxy-3-phenylpropyl)-L-phenylalanyl-L-proline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Oxo-4-phenylbutyric acid | HCID 69732 | — |
| Reactant | Sodium cyanoborohydride | HCID 5003444 | — |
| Reactant | Phe-Pro | HCID 7020642 | — |
| Product | N-(1-carboxy-3-phenylpropyl)-L-phenylalanyl-L-proline | HCID 54222365 | — |
Reaction Steps
In the manner described in example 24, 2-oxo-4-phenylbutyric acid and L-phenylalanyl-L-proline are condensed in the presence of sodium cyanoborohydride to yield N-(1-carboxy-3-phenylpropyl)-L-phenylalanyl-L-proline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04472380 |
| Source dataset | uspto-grants-1984_09 |
| ORD ID | ord-0c09241938134133a5c38473b418efc2 |
| Source note | uspto-grants-1984_09 |