反应详情

250 mL flask was charged with 6-benzyl-4-methoxy-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine (4.08 g, 16.0 mmol), 10% palladium on charcoal (400 mg) and methanol (100 mL). The reaction was evacuated and purged with hydrogen three times, and hydrogenated (1 atm) overnight. The mixture was filtered through a “Dry disk” membrane filter, and concentrated in vacuo to give an orange oil (2.56 g).

1. customThe reaction was evacuated
2. custompurged with hydrogen three times, and hydrogenated (1 atm) overnight
3. filtrationThe mixture was filtered through a “
4. customDry disk” membrane
5. filtrationfilter
6. concentrationconcentrated in vacuo