m-Chloroperbenzoic acid → HCID 22351550, compound

Participants

Reaction Steps

To a solution of 25.4 g (0.1 mole) of the lactam compound prepared in Example 1 in 200 ml of chloroform is added portionwise 38 g (0.22 mole) of m-chloroperbenzoic acid over a one-hour period. The reaction mixture is stirred for an eighteen-hour period at ambient temperature. The mixture is then filtered to remove the m-chlorobenzoic acid formed. The filtrate is washed successively with 1N sulfuric acid, with water and with 10% aqueous sodium bicarbonate and then dried. The solvent is removed in vacuo and the residue recrystallized from tolueneheptane to give the above-named compound as an orange solid melting at 158°-164° C.

Provenance & Evidence