反应详情

A mixture of 2.63 g of ethyl 1,4-dihydro-1,4-dioxo-3-methoxy-2-naphthoate and 1.3 g of o-phenylenediamine in 50 ml of ethanol was heated at reflux for an hour. After cooling, the precipitated solid was collected by filtration and recrystallized from ethanol to give 2.972 g (93.5% yield) of ethyl 5-hydroxybenzo[a]phenazine-6-carboxylate as yellow needles, m.p. 126°-127° C., Anal. CAlcd. (%) for C19H14N2O3 : C, 71.69; H, 4.43; N, 8.80; Found: C, 71.81; H, 4.21; N, 8.90

1. temperaturewas heated
2. temperatureat reflux for an hour
3. temperatureAfter cooling
4. filtrationthe precipitated solid was collected by filtration
5. customrecrystallized from ethanol