HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetophenone → Ethyl 2-(2-Butyl)-3-hydroxy-3-methyl-3-phenylpropionate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetophenone | HCID 7410 | — |
| Reactant | Ethyl 3-methylpentanoate | HCID 560255 | — |
| Product | Ethyl 2-(2-Butyl)-3-hydroxy-3-methyl-3-phenylpropionate | HCID 13742288 | 36% |
Reaction Steps
The reaction of acetophenone (12 grams, 0.1 mole) with the enolate of ethyl 3-methylvalerate (14.4 grams, 0.1 mole) is carried out in the manner described in Example I. Distillation yields 9.5 grams (36%) of the pure product, b.p. 75°-80° C. (air bath temperature) at 0.05 mm Hg. I.R., N.M.R. and M.S. data confirm the above structure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04473085 |
| Source dataset | uspto-grants-1984_09 |
| ORD ID | ord-b8b9398871194129b91d33b382191fdd |
| Source note | uspto-grants-1984_09 |