Acetic Acid → HCID 20445350, compound

Participants

Reaction Conditions

Reaction Steps

A solution of acetic acid (70 ml) containing 21 g (0.0287 mol) of the compound obtained in Step (c) above, 15 ml of acetic anhydride and 9.8 g of sodium acetate was stirred at 80° C. for 2 hours. After cooling, the reaction mixture was added to 500 ml of water and the precipitate was extracted with ethyl acetate. The ethyl acetate was concentrated and to the residue was added 100 ml of methanol and the crystals thus-precipitated were collected by filtration. Yield: 20.6 g (93%).

Provenance & Evidence