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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2418849Generated: October 25, 2026

Cyclohexanecarboxylic acid → 1-Cyclohexyl-5-(1,4-diazepan-1-ylsulfonyl)isoquinoline

https://huagongshe.com/reaction/2418849

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclohexanecarboxylic acidHCID 7413—
ReactantFasudil HydrochlorideHCID 163751—
ReagentCID 21864320HCID 21864320—
SolventDimethyl SulfoxideHCID 679—
SolventWaterHCID 962—
Product1-Cyclohexyl-5-(1,4-diazepan-1-ylsulfonyl)isoquinolineHCID 17825127144%

Reaction Conditions

Temperature40 °C

Provenance & Evidence

DOI10.1021/acs.orglett.8b02988
Source datasetMinisci dataset from Roche
ORD IDord-96470e19347144c3a3f2eb02aafad67c
Source noteMinisci dataset from Roche