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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2418860Generated: October 25, 2026

2-Mercaptobenzothiazole → 2-[(Difluoromethyl)sulfanyl]-1,3-benzothiazole

https://huagongshe.com/reaction/2418860

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MercaptobenzothiazoleHCID 697993—
ReactantHCID 89600919HCID 89600919—
Reagenttert-Butyl hydroperoxideHCID 6410—
ReagentTrifluoroacetic acidHCID 6422—
SolventWaterHCID 962—
SolventDichloromethaneHCID 6344—
Product2-[(Difluoromethyl)sulfanyl]-1,3-benzothiazoleHCID 152232761%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1021/ja211422g
Source datasetMinisci dataset from Roche
ORD IDord-1a22e1193ad948cb95e32e804572836c
Source noteMinisci dataset from Roche