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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2418897Generated: October 26, 2026

3-Acetyl-5-bromopyridine → 1-(5-Bromo-6-isopropylpyridin-3-yl)ethan-1-one

https://huagongshe.com/reaction/2418897

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Acetyl-5-bromopyridineHCID 820423—
ReactantPropane-2-sulfinic acid;ZINCHCID 117778686—
Reagenttert-Butyl hydroperoxideHCID 6410—
SolventWaterHCID 962—
SolventAnisoleHCID 7519—
Product1-(5-Bromo-6-isopropylpyridin-3-yl)ethan-1-oneHCID 7552987441%

Reaction Conditions

Temperature50 °C

Provenance & Evidence

DOI10.1038/nature11680
Source datasetMinisci dataset from Roche
ORD IDord-326f55e501a44a0c9280dadd1dc989c1
Source noteMinisci dataset from Roche