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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2418898Generated: October 26, 2026

Caffeine → 1,3,7-Trimethyl-8-(propan-2-yl)-3,7-dihydro-1h-purine-2,6-dione

https://huagongshe.com/reaction/2418898

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCaffeineHCID 2519—
ReactantPropane-2-sulfinic acid;ZINCHCID 117778686—
Reagenttert-Butyl hydroperoxideHCID 6410—
SolventDimethyl SulfoxideHCID 679—
SolventWaterHCID 962—
Product1,3,7-Trimethyl-8-(propan-2-yl)-3,7-dihydro-1h-purine-2,6-dioneHCID 26560541%

Reaction Conditions

Temperature50 °C

Provenance & Evidence

DOI10.1038/nature11680
Source datasetMinisci dataset from Roche
ORD IDord-ea7c4b71a086469394a4a7c53223042b
Source noteMinisci dataset from Roche