2,2,6,6-Tetramethyl-4-piperidone → 1,6-Bis(2,2,6,6-tetramethyl-4-piperidylamino)hexane

HRID 2418964Notes

Reaction equation

HRID 2418964 reaction equation
[CH3:1][C:2]1([CH3:11])[CH2:7][C:6](=O)[CH2:5][C:4]([CH3:10])([CH3:9])[NH:3]1.[NH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][NH2:19]>CO>[CH3:1][C:2]1([CH3:11])[CH2:7][CH:6]([NH:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][NH:19][CH:6]2[CH2:5][C:4]([CH3:10])([CH3:9])[NH:3][C:2]([CH3:11])([CH3:1])[CH2:7]2)[CH2:5][C:4]([CH3:10])([CH3:9])[NH:3]1

Participants

4

Reactant 2

HCID 132202,2,6,6-Tetramethyl-4-piperidoneHCID 16402Hexamethylenediamine

Product 1

HCID 934191,6-Bis(2,2,6,6-tetramethyl-4-piperidylamino)hexane

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

162.75 g (1.05 moles) of 2,2,6,6-tetramethyl-4-piperidone dissolved in 200 cc of methanol, 58 g (0.5 moles) of hexamethylenediamine dissolved in 70 cc of methanol, and 0.5 g of Pt (at 10% on carbon) were introduced into a 1 liter autocalve. The mixture was hydrogenated at 80° C and 50 atm pressure for 2 hours.

Workup

  1. customwas hydrogenated at 80° C

Sources & evidence

ORD record
ord-1281239a69984d01ad3281d87f31a175
Source dataset
uspto-grants-1978_08
Patent number
US04104248

Reaction notes

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