Thionyl Chloride → 3-(2-Chloroethanesulfonyl)propanoyl chloride

HRID 2418989Notes

Reaction equation

HRID 2418989 reaction equation
[Cl:1][CH2:2][CH2:3][S:4]([CH2:7][CH2:8][C:9]([OH:11])=O)(=[O:6])=[O:5].S(Cl)([Cl:14])=O>>[Cl:1][CH2:2][CH2:3][S:4]([CH2:7][CH2:8][C:9]([Cl:14])=[O:11])(=[O:6])=[O:5]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 51037803884-76-2

Product 1

HCID 136683973-(2-Chloroethanesulfonyl)propanoyl chloride

Procedure

20 g of 3-(2-chloroethylsulphonyl)-propionic acid was mixed with 70 ml thionyl chloride and the mixture refluxed for 2 hours. Excess thionyl chloride was distilled off under reduced pressure and the product recrystallised from benzene/petrol.

Workup

  1. temperaturethe mixture refluxed for 2 hours
  2. distillationExcess thionyl chloride was distilled off under reduced pressure
  3. customthe product recrystallised from benzene/petrol

Sources & evidence

ORD record
ord-286b42ba37ca4abc804de3225b82da50
Source dataset
uspto-grants-1978_08
Patent number
US04104302

Reaction notes

Loading…