Methyl 2-Bromo-3-methylbenzoate → HCID 86735878, compound

HRID 2419026Notes

Reaction equation

HRID 2419026 reaction equation
BrC1C(C)=CC=CC=1[C:4]([O:6][CH3:7])=[O:5].[C:13]1([CH:19]2[CH2:24][NH:23][CH2:22][C:21]3[S:25][CH:26]=[CH:27][C:20]2=3)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[CH3:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33].[CH2:34]1CCCCC1>>[CH3:7][O:6][C:4]([C:27]1[C:20]2[CH:19]([C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=3)[CH2:24][NH:23][CH2:22][C:21]=2[S:25][C:26]=1[CH2:34][C:30]1[CH:29]=[CH:28][CH:33]=[CH:32][CH:31]=1)=[O:5]

Participants

4

Reactant 3

HCID 10823279Methyl 2-Bromo-3-methylbenzoateHCID 127369914-Phenyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridineHCID 22494920Cyclohexane hexane

Product 1

HCID 86735878HCID 86735878, compoundYield 68%

Procedure

Methyl 2-bromo-methyl-benzoate is condensed with 4-phenyl-4,5,6,7-tetrahydro-thieno[2,3-c]pyridine (Example 3), according to the procedure of Example 8. Base: M.p. = 90° C (hexane-cyclohexane); Yield: 68%.

Sources & evidence

ORD record
ord-566c675464a04c8f9441472a337fbb60
Source dataset
uspto-grants-1978_08
Patent number
US04104390

Reaction notes

Loading…