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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2419061Generated: November 3, 2026

1-Cyano-2,3-dimethylisothiourea → HCID 178513029, compound

https://huagongshe.com/reaction/2419061

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Cyano-2,3-dimethylisothioureaHCID 111103—
Reactant2-[(Thiazol-2-yl)methylthio]ethylamineHCID 12923403—
ProductHCID 178513029HCID 178513029—

Reaction Steps

Reaction of [(2-aminoethyl)thiomethyl]thiazole (from the dihydrobromide 20.2 g) with N-cyano-N',S-dimethylisothiourea (7.75 g) by a procedure similar to that described in Example 75, afforded N-cyano-N'-methyl-N"-[(2-(2-thiazolylmethylthio)ethyl]guanidine, m.p. 120°-122.5°, following chromatography on silica gel with alcohol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04104382
Source datasetuspto-grants-1978_08
ORD IDord-56619db7a83747d5b3dad64b9528eca4
Source noteuspto-grants-1978_08