Cyclopentanone → HCID 12390926, compound

HRID 2419082Notes

Reaction equation

HRID 2419082 reaction equation
[ClH:1].[NH2:2][CH:3]1[CH2:12][CH2:11][C:10]2[C:5](=[CH:6][CH:7]=[C:8]([O:15][CH3:16])[C:9]=2[O:13][CH3:14])[C:4]1=[O:17].[C:18]1(=O)[CH2:22][CH2:21][CH2:20][CH2:19]1>>[ClH:1].[CH:18]1([NH:2][CH:3]2[CH2:12][CH2:11][C:10]3[C:5](=[CH:6][CH:7]=[C:8]([O:15][CH3:16])[C:9]=3[O:13][CH3:14])[C:4]2=[O:17])[CH2:22][CH2:21][CH2:20][CH2:19]1

Participants

3

Reactant 2

HCID 8452CyclopentanoneHCID 12353614HCID 12353614, compound

Product 1

HCID 12390926HCID 12390926, compound

Procedure

In a manner similar to that of Reference Example 3, 10 parts of 2-amino-5,6-dimethoxy-3,4-dihydro-1(2H)-naphthalenone hydrochloride is reacted with 300 volume parts of cyclopentanone. The procedure yields 10.2 parts of 2-cyclopentylamino-5,6-dimethoxy-3,4-dihydro-1(2H)-naphthalenone hydrochloride as colorless crystals melting at 158°-167° C (decomposition).

Sources & evidence

ORD record
ord-acfc77925d3145deace7deee7d78b338
Source dataset
uspto-grants-1978_08
Patent number
US04104402

Reaction notes

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