HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2419140Generated: November 1, 2026
Dimethylformamide → 3-[(5-Chloro-1,3-benzodithiol-2-ylidene)amino]-2-thioxo-4-thiazolidinone
https://huagongshe.com/reaction/2419140
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 3-Aminorhodanine | HCID 74033 | — |
| Reactant | 5-Chloro-N-methyl-N-phenyl-1,3-benzodithiol-2-iminium iodide | HCID 20313844 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-[(5-Chloro-1,3-benzodithiol-2-ylidene)amino]-2-thioxo-4-thiazolidinone | HCID 73676072 | 79% |
Reaction Steps
A mixture of the methiodide of 5-chloro-N-methyl-N-phenyl-1,3-benzodithiol-2-iminium iodide (1.9 g), sodium carbonate (121 mg), N-aminorhodanine (338 mg) and dimethylformamide (20 ml) is heated at 50° C for 3 hours. The mixture is poured into water and the precipitate which forms is filtered and washed with water. The product is recrystallized from dimethylformamide to yield 600 mg of the title compound, melting point 312°-314° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04104467 |
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| Source dataset | uspto-grants-1978_08 |
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| ORD ID | ord-e3e871ef7ecb4fb68e413882d542ce55 |
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| Source note | uspto-grants-1978_08 |
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