HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylacetaldehyde → 3-(1,3-Benzodithiol-2-ylideneamino)-5-(2-phenylethylidene)-2-thioxo-4-thiazolidinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylacetaldehyde | HCID 998 | — |
| Reactant | 3-[(1,3-Benzodithiol-2-ylidene)amino]-2-thioxo-4-thiazolidinone | HCID 12494993 | — |
| Catalyst | Piperidine, acetate | HCID 9793820 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | 3-(1,3-Benzodithiol-2-ylideneamino)-5-(2-phenylethylidene)-2-thioxo-4-thiazolidinone | HCID 73998102 | — |
Reaction Steps
A slurry of 2.98 g of 3-[(1,3-benzodithiol-2-ylidene)amino]-2-thioxo-4-thiazolidinone (see example 37), phenylacetaldehyde (10 ml, excess) and acetic acid/piperidine (10 drops) in 600 ml of anhydrous glyme is heated at reflux for four days. The reaction mixture is filtered while hot, and the solid is collected and recrystallized from dimethylformamide to yield 1.78 g of the title compound, melting point 233°-234° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04104467 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-feda2da6920f41aeb1a15ecdf46c5539 |
| Source note | uspto-grants-1978_08 |