Thionyl Chloride → HCID 53703656, compound

HRID 2419192Notes

Reaction equation

HRID 2419192 reaction equation
[Cl:1][CH:2]([C:13]#[N:14])[CH2:3][C:4]1[CH:12]=[CH:11][CH:10]=[CH:9][C:5]=1[C:6](O)=[O:7].S(Cl)([Cl:17])=O>C1(C)C=CC=CC=1>[Cl:1][CH:2]([C:13]#[N:14])[CH2:3][C:4]1[CH:12]=[CH:11][CH:10]=[CH:9][C:5]=1[C:6]([Cl:17])=[O:7]

Participants

4

Reactant 2

HCID 24386Thionyl Chloride2×HCID 20315068HCID 20315068, compound

Product 1

HCID 53703656HCID 53703656, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent2×

Procedure

209.5 parts of 2-(2-chloro-2-cyanoethyl) benzoic acid are made into a paste in 220 parts of toluene and 125 parts of thionyl chloride and the mixture is refluxed until the acid completely dissolves. Then the surplus thionyl chloride and toluene are eliminated under reduced pressure. 2-(2-chloro-2-cyanoethyl) benzoyl chloride is obtained which is liquid at normal temperature.

Workup

  1. temperaturethe mixture is refluxed until the acid
  2. dissolutioncompletely dissolves

Sources & evidence

ORD record
ord-4f2458258939402eb183eab8fba40740
Source dataset
uspto-grants-1978_08
Patent number
US04105653

Reaction notes

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