HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → 2-Amino-10,11-dihydro-dibenz[b,f]oxepin-10-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 10,11-Dihydro-2-nitro-dibenz[b,f]oxepin-10-one | HCID 22767855 | — |
| Catalyst | Platinum oxide (PtO) | HCID 82844 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Amino-10,11-dihydro-dibenz[b,f]oxepin-10-one | HCID 22767927 | — |
Reaction Steps
52.5 G. of 10,11-dihydro-2-nitro-dibenz[b,f]oxepin-10-one are suspended in 900 ml. of ethyl acetate and 450 ml. of ethanol and hydrogenated in the presence of 300 mg. of platinum oxide at room temperature and normal pressure. The catalyst is removed by filtration, the filtrate evaporated in vacuo. The residue is crystallized from benzene/hexane, and there is obtained 2-amino-10,11-dihydro-dibenz-[b,f]oxepin-10-one having a melting point of 116°-117° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04105664 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-e56aac709e304bcca518dfade3d42b91 |
| Source note | uspto-grants-1978_08 |