HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Nitro 6-(2-pyridylthio) imidazo [1,2-a] pyridine → 3-Amino-6-(2-pyridylthio) imidazo [1,2-a] pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Nitro 6-(2-pyridylthio) imidazo [1,2-a] pyridine | HCID 53863063 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 3-Amino-6-(2-pyridylthio) imidazo [1,2-a] pyridine | HCID 54200043 | — |
Reaction Steps
A solution of 0.542 gm. (0.002 mole) of 3-nitro-6-(2-pyridylthio) imidazo [1,2-a] pyridine in 20 ml. of dioxane is reduced at 40 psi. under a hydrogen atmosphere with 0.500 g. of 5% palladium on carbon as catalyst. When the uptake of hydrogen is complete, the catalyst is removed by filtration. The filtrate is evaporated in vacuo to yield 3-amino-6-(2-pyridylthio) imidazo [1,2-a] pyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04105767 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-967c8f69950643039b2a69ede23bb25c |
| Source note | uspto-grants-1978_08 |