p-Toluenesulfonic acid monohydrate → p-Toluenesulfonic acid

Participants

Reaction Steps

To a stirred solution of 0.422 g. (0.75 mmole) of 6-(triphenylmethylamino)-2,2-dimethyl-3(1-furfuryltetrazol-5-yl)penam in 1 ml of acetone at ambient temperature, is added 0.142 g. (0.75 mmole) of p-toluenesulfonic acid monohydrate. Stirring is continued for 30 minutes, and then the solvent is removed by evaporation in vacuo. This affords the title compound as its p-toluenesulfonate salt. IR (Nujol mull): 1780 cm-1 (B-lactam). NMR (DMSO-d6): 7.20 ppm (q,4H), 6.40 ppm (m,2H), 5.90 ppm (s,2H), 5.60 ppm (m,2H), 5.00 ppm (d,1H), 2.20 ppm (s,3H), 1.60 ppm (s,3H), 0.80 ppm (s,3H).

Provenance & Evidence