反应详情

A solution of sodium azide (2.0g.) in water (20ml.) was added to a stirred suspension of 3-[4-(chloroacetyl)phenyl]-propionic acid (5g.) in water (30ml.). After stirring for 16 hours at room temperature, the residual solid was separated, washed with cold water (2 × 10ml.) and dried in vacuo to give 3-[4-(azidoacetyl)phenyl]propionic acid as a white solid, which possessed a characteristic azide absorption in the infra-red spectrum at 2120 cm-1.

1. customthe residual solid was separated
2. washwashed with cold water (2 × 10ml.)
3. customdried in vacuo