HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → Methyl 4-[4-(chloroacetyl)phenoxy]butyrate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | Methyl 4-phenoxybutanoate | HCID 568131 | — |
| Reactant | 3-[4-(Chloroacetyl)phenyl]propionic acid | HCID 20315571 | — |
| Product | Methyl 4-[4-(chloroacetyl)phenoxy]butyrate | HCID 20315580 | — |
Reaction Steps
Methyl 4-phenoxybutyrate was reacted with acetyl chloride in a similar manner to that described above for 3-[4-(chloroacetyl)phenyl]propionic acid, except that the crude product was triturated with petrol to give methyl 4-[4-(chloroacetyl)phenoxy]butyrate as a crystalline solid which was pure by TLC analysis (on silica plates; eluant: 50% ether/50% petrol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04105790 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-9689b62e9f2347318eed30e79ef37ac8 |
| Source note | uspto-grants-1978_08 |