HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diazomethane → 1-[3-(ethyldithio)-2-methylpropanoyl]-L-proline methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diazomethane | HCID 9550 | — |
| Reactant | 1-(3-Mercapto-1-oxopropyl)-L-proline | HCID 99978 | — |
| Reactant | 1-(2-Methyl-3-sulfanylpropanoyl)-L-proline | HCID 12877547 | — |
| Product | 1-[3-(ethyldithio)-2-methylpropanoyl]-L-proline methyl ester | HCID 53935199 | — |
Reaction Steps
By substituting 1-(3-mercapto-2-methylpropanoyl)-L-proline for the 3-mercaptopropanoyl-L-proline in the procedure of Example 97 and then treating the product with ethereal diazomethane as in the procedure of Example 72, 1-[3-(ethyldithio)-2-methylpropanoyl]-L-proline methyl ester is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04105776 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-2ef0147d4b154129b95e640008393175 |
| Source note | uspto-grants-1978_08 |