1-(3-Mercapto-1-oxopropyl)-L-proline → HCID 21319157, compound
Reaction equation
[SH:1][CH2:2][CH2:3][C:4]([N:6]1[CH2:14][CH:13]([OH:15])[CH2:12][CH2:11][CH:7]1[C:8]([OH:10])=[O:9])=[O:5].[SH:16][CH2:17][CH2:18]C(N1CCC[C@H]1C(O)=O)=O>>[CH2:17]([S:16][S:1][CH2:2][CH2:3][C:4]([N:6]1[CH2:14][CH:13]([OH:15])[CH2:12][CH2:11][CH:7]1[C:8]([OH:10])=[O:9])=[O:5])[CH3:18]Participants
3
Procedure
By substituting 1-(3-mercaptopropanoyl)-5-hydroxy-L-pipecolic acid for the 3-mercaptopropanoyl-L-proline in the procedure of Example 97, 1-[3-(ethyldithio)propanoyl]-5-hydroxy-L-pipecolic acid is obtained.
Sources & evidence
- ORD record
- ord-99ed06f66e744826893966025cbf4af6
- Source dataset
- uspto-grants-1978_08
- Patent number
- US04105776
Reaction notes
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