HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-mercaptopropanoyl-L-proline-t-butyl ester → 1-(2-Methyl-3-sulfanylpropanoyl)-L-proline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-mercaptopropanoyl-L-proline-t-butyl ester | HCID 13208321 | — |
| Reactant | N-(3-Mercapto-2-methylpropanoyl)-L-Proline tert-butyl Ester | HCID 54491354 | — |
| Product | 1-(2-Methyl-3-sulfanylpropanoyl)-L-proline | HCID 12877547 | — |
Reaction Steps
By substituting 1-(3-mercapto-2-methylpropanoyl)-L-proline tert. butyl ester for the 1-(3-mercaptopropanoyl-L-proline tert.butyl ester in the procedure of Example 18C, 1-(3-mercapto-2-methylpropanoyl)-L-proline is obtained. Rf 0.35 (Silica gel, Benzene/acetic acid 3:1), Rf 0.5 (Silica gel, Methyl-ethylketone/Acetic acid/Pyridine/Water 14:1:2:1), identical to the compound of Example 34.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04105776 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-3f0578b960824f1886fbf27396f622d7 |
| Source note | uspto-grants-1978_08 |