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HRID2419488

反应详情

EQUATION

反应方程式

HRID 2419488 的结构方程式

REACTANTS

反应物

2
反应SMILES：NN
HCID9321

Hydrazine

H4N2

反应SMILES：CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](COCc1ccccc1)NC(=O)OC(C)(C)C)[C@@H](C)OCc1ccccc1)C(=O)N[C@H](C(=O)N[C@H](C(=O)OCc1ccccc1)[C@@H](C)OCc1ccccc1)C(C)C
HCID131711192

未命名化合物

PRODUCTS

产物

1
反应SMILES：CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](COCc1ccccc1)NC(=O)OC(C)(C)C)[C@@H](C)OCc1ccccc1)C(=O)N[C@H](C(=O)N[C@H](C(=O)NN)[C@@H](C)OCc1ccccc1)C(C)C
HCID131711191

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
反应SMILES：CN(C)C=O.CO
溶剂HCID21901440

未命名化合物

PROCEDURE

实验过程

Compound XIV (1.6 g, 1.32 mmol) was dissolved in DMF/MeOH (5:3; 16 ml) and treated with H2NNH2 (0.78 ml) for 72 hrs at 25° C. The white solid was filtered and washed with MeOH and water, yield 1.05 g (70.5%); mp 210°-210.5° C; [α]D25 -22.5° (c 1, DMF). Anal. Calcd for C58H84N10O13 (1129.37): C, 61.68; H, 7.50; N, 12.40. Found: C, 61.72; H, 7.26; N, 12.30.

WORKUP

后处理

  1. filtrationThe white solid was filtered
  2. washwashed with MeOH and water, yield 1.05 g (70.5%)