HCID 4408645, compound → HCID 20313392, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 5.2 g of ethyl (2-phenylthio-2-methylpropionyl)acetate obtained in Step 1 of Synthesis Example 8 and 8.8 g of 2-chloro-5-[2-(2,4-di-tert-amylphenoxy)butyramido]aniline was stirred in an oil bath at 150° C for three hours under a reduced pressure of 15 to 20 mmHg. The reaction mixture was recrystallized from n-hexane to obtain 9.8 g (yield 75%) of Coupler (17) having a melting point of 73° to 75° C.

Provenance & Evidence