HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorobenzotrichloride → Benzoxazole, 5-chloro-2-(4-chlorophenyl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorobenzotrichloride | HCID 21277 | — |
| Reactant | Phenol, 2-amino-4-chloro-, hydrochloride (1:1) | HCID 165320 | — |
| Product | Benzoxazole, 5-chloro-2-(4-chlorophenyl)- | HCID 548468 | — |
Reaction Steps
Compound XIV was prepared as in Example 12 at 180° C from p-chlorobenzotrichloride and 2-amino-4-chlorophenol hydrochloride, and purified through a preheated aluminum trioxide column: 16 g of raw product, M.P. 178°-183° C (61% of the theory). Upon recrystallization from benzene: M.P. 190°-192° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04107169 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-47fcb5c3ddfc43a4a3f79153bd75a1ad |
| Source note | uspto-grants-1978_08 |