HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorobenzotrichloride → 2-(4-Chlorophenyl)-5-nitrobenzoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorobenzotrichloride | HCID 21277 | — |
| Reactant | Phenol, 2-amino-4-nitro-, hydrochloride | HCID 5745966 | — |
| Product | 2-(4-Chlorophenyl)-5-nitrobenzoxazole | HCID 483838 | — |
Reaction Steps
Compound XV was prepared as in Example 12 at 180°-200° C from p-chlorobenzotrichloride and 2-amino-4-nitrophenol hydrochloride, and purified through a preheated Al2O3 column: 3.4 g of raw product melting at 205°-210° C (12% of the theory). After recrystallization from benzene: melting point 217°-218° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04107169 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-c271b461746642cabcd14113ab89bfc1 |
| Source note | uspto-grants-1978_08 |