反应详情

A slurry of 2.0g of 3-[(1,3-benzodithiol-2-ylidene)amino]- 2-thioxo-4-thiazolidinone (see example 37), valeraldehyde (10 ml, excess) and acetic acid/piperidine (2:1) (10 drops) in anhydrous slyme (400 ml) is heated at reflux for eighteen hours. The reaction mixture is chilled in an ice bath and the resultant precipitate collected by filtration. This precipitate (1.6 g) is recrystallized from 50 ml of dimethylformamide to yield 1.1 g of the title compound, melting point 210°-212° C.

1. temperatureat reflux for eighteen hours
2. temperatureThe reaction mixture is chilled in an ice bath
3. filtrationthe resultant precipitate collected by filtration
4. customThis precipitate (1.6 g) is recrystallized from 50 ml of dimethylformamide