反应详情

A slurry of 2.0g of 3-[(1,3-benzodithiol-2-ylidene)amino]- 2-thioxo-4-thiazolidinone (see example 37), octanal (15 ml, excess) and acetic acid/piperidine (10 drops) in anhydrous glyme (400 ml) is heated at reflux for 18 hours. The reaction mixture is chilled in an ice bath and the resultant precipitate collected by filtration. The precipitate is recrystallized twice from dimethylformamide to yield 1.02g of the title compound, melting point 185° C.

1. temperatureat reflux for 18 hours
2. temperatureThe reaction mixture is chilled in an ice bath
3. filtrationthe resultant precipitate collected by filtration
4. customThe precipitate is recrystallized twice from dimethylformamide