HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylacetaldehyde → 3-(1,3-Benzodithiol-2-ylideneamino)-5-(2-phenylethylidene)-2-thioxo-4-thiazolidinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylacetaldehyde | HCID 998 | — |
| Reactant | 3-[(1,3-Benzodithiol-2-ylidene)amino]-2-thioxo-4-thiazolidinone | HCID 12494993 | — |
| Catalyst | Piperidine, acetate | HCID 9793820 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | 3-(1,3-Benzodithiol-2-ylideneamino)-5-(2-phenylethylidene)-2-thioxo-4-thiazolidinone | HCID 73998102 | — |
Reaction Steps
A slurry of 2.98g of 3-[(1,3-benzodithiol-2-ylidene)amino] -2-thioxo-4-thiazolidinone (see example 37), phenylacetaldehyde (10 ml, excess) and acetic acid/piperidine (10 drops) in 600 ml of anhydrous glyme is heated at reflux for 4 days. The reaction mixture is filtered while hot, and the solid is collected and recrystallized from dimethylformamide to yield 1.78 g of the title compound, melting point 233°-234° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04107175 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-a77cef40f68a487f8dfcc0e2bee35980 |
| Source note | uspto-grants-1978_08 |